Publications

National Center of Pathology

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Integrative genomic and transcriptomic profiles from a prospective cervical cancer study (RAIDs).
Maud Kamal; Solenn Barraud; Lolita Lecompte; Maral Halladjian; Emmanuelle Jeannot; Elodie Girard; Sylvain Baulande; Patricia Legoix; Fabrice Lecuru; Léa Pauly; Mathilde Saint-Ghislain; Stacy Cyrille; Célia Dupain; Constance Lamy; Olfa Chouchane-Mlik; Alexandra Oniga; Michel Mittelbronn; Christophe Le Tourneau; Aurélien Latouche; Nicolas Servant; Suzy Scholl; Ivan Bièche.
The role of [18 F]FDOPA PET as an adjunct to conventional MRI in the diagnosis of aggressive glial lesions. Zinsz A, Pouget C, Rech F, Taillandier L, Blonski M, Amlal S, Imbert L, Zaragori T, Verger A. Eur J Nucl Med Mol Imaging. 2024 Jul;51(9):2672-2683. doi: 10.1007/s00259-024-06720-y. Epub 2024 Apr 19. PMID: 38637354.
Staging of endometrial cancer. An illustrated guide to understand and apply the 2023 FIGO system. A. García Bolado, E. Julián Gómez, D. Val Garijo. Radiología, 2024, ISSN 0033-8338. https://doi.org/10.1016/j.rx.2024.06.004.
Systematic assessment of tumor necrosis at baseline in cervical cancer – An independent factor associated with poor outcome. Chouchane-Mlik O, Oniga A, Latouche A, Halladjian M, Kleine-Borgmann FB, Gérardy JJ, Mittelbronn M, Kamal M, Scholl SM. Hum Pathol. 2024 Jan;143:62-70. doi: 10.1016/j.humpath.2023.12.003. Epub 2023 Dec 20. PMID: 38135059.
Digital cytology with machine learning compared to conventional microscopy for anal cytology: A preliminary study. Rene Gerhard; Cioly Rivero Colmenarez; Gaël Hammer; Corinne Selle. Cytopathology. 2024;35(Suppl. 1):5–44. DOI: 10.1111/cyt.13404
International Society of Urological Pathology Consensus Conference on Current Issues in Bladder Cancer. Working Group 4: Molecular Subtypes of Bladder Cancer-Principles of Classification and Emerging Clinical Utility. Joshua I Warrick 1 , Hikmat Al-Ahmadie 2 , David M Berman 3 , Peter C Black 4 , Thomas W Flaig 5 , Mattias Höglund 6 , Lukas Bubendorf 7 , Theodorus H van der Kwast 8 , Liang Cheng 9 ; Members of the ISUP Bladder Tumor Consensus Panel. Collaborators : * Members of the ISUP Bladder Tumor Consensus Panel: Adebowale Adeniran, Hikmat Al-Ahimadie, Fernando Algaba, Yves Allory, Selina Bhattarai, Peter Black, David Berman, Simone Bertz, Lukas Bubendorf, Birgitte Carlsen, Rita Carvalho, Liang Cheng, Obinna Chijioke, Yong Mee Cho, Eva Comperat, Isabela di Cunha, Julien Dagher, Isabella de Cunha, Brett Delahunt, Michelle Downes, Thomas Flaig, Achim Fleischmann, Cosmin Florescu, Jacqueline Fontugne, Vera Genitsch, Guro Horni Gløersen, Michael von Gunten, Rainer Grobholz, Donna HanselArndt Hartmann, Loren Herrera Hernandez, Mattias Hogland, Jiaoti Huang, Brad Jensen, Kenneth Iczkowski, Rafael Jimenez, Bojana Jovanovic, Ashish Kamat, Jens Koellermann, Trevor Levin, Fredrik Liedberg, Antonio Lopez-Beltran, Anand C Loya, Marianne Lyngra, Teresa McHale, Khadidja Mokeddem, George Netto, Maya Nourieh, Declan O’Rourke, Irina-Alexandra Ostahi, Gladell Paner, Maria M Picken, Flavia Guzman Pineda, Camelia Radulescu Maria Raspollini, Henning Reis, Shi Ruoyu, Hemamali Samaratunga, Remi Semba, Nigam Shah, Steven Shen, Steven Smith, Tovia Smith, John Srigley, Sueli Suzigan, Nicole Swarbrick, Ildiko Szalay, Inger Talleraas, Jean-Christophe Tille, Marieta Toma, Isabel Trias, Toyonori Tsuzuki, Theodorus van der Kwast, Bas van Rhijn, Murali Varma, Sofie Verbeke, Sangeeta Verma, Tatjana Vlajnic, Ljiljana Vlatkovic, Anne Warren, Joshua Warrick, Sean Williamson, Sara Wobker, Clifton Woods, Chen Yang, Ghilsuk Yoon.
Neurooncology: 2024 update. Mittelbronn M. Free Neuropathol. 2024 Sep 27;5:21. doi: 10.17879/freeneuropathology-2024-5809. eCollection 2024 Jan. PMID: 39385753 .
Metformin impacts the differentiation of mouse bone marrow cells into macrophages affecting tumour immunity. Scafidi A, Lind-Holm Mogensen F, Campus E, Pailas A, Neumann K, Legrave N, Bernardin F, Pereira SL, Antony PMA, Nicot N, Mittelbronn M, Grünewald A, Nazarov PV, Poli A, Van Dyck E, Michelucci A. Heliyon. 2024 Sep 11;10(18):e37792. doi: .1016/j.heliyon.2024.e37792. eCollection 2024 Sep 30. PMID: 39315158
A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.
Bonetti L, Horkova V, Grusdat M, Longworth J, Guerra L, Kurniawan H, Franchina DG, Soriano-Baguet L, Binsfeld C, Verschueren C, Spath S, Ewen A, Koncina E, Gérardy JJ, Kobayashi T, Dostert C, Farinelle S, Härm J, Fan YT, Chen Y, Harris IS, Lang PA, Vasiliou V, Waisman A, Letellier E, Becher B, Mittelbronn M, Brenner D. Cell Metab. 2024 Aug 6;36(8):1726-1744.e10. doi: 10.1016/j.cmet.2024.06.010. Epub 2024 Jul 9. PMID: 38986617
Machine Learning-Assisted Classification of Paraffin-Embedded Brain Tumors with Raman Spectroscopy. Klamminger GG, Mombaerts L, Kemp F, Jelke F, Klein K, Slimani R, Mirizzi G, Husch A, Hertel F, Mittelbronn M, Kleine Borgmann FB. Brain Sci. 2024 Mar 23;14(4):301. doi: 10.3390/brainsci14040301. PMID: 38671953 .
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts. Yabo YA, Moreno-Sanchez PM, Pires-Afonso Y, Kaoma T, Nosirov B, Scafidi A, Ermini L, Lipsa A, Oudin A, Kyriakis D, Grzyb K, Poovathingal SK, Poli A, Muller A, Toth R, Klink B, Berchem G, Berthold C, Hertel F, Mittelbronn M, Heiland DH, Skupin A, Nazarov PV, Niclou SP, Michelucci A, Golebiewska A. Genome Med. 2024 Apr 2;16(1):51. doi: 10.1186/s13073-024-01321-8. PMID: 38566128
Glioma subtype classification from histopathological images using in-domain and out-of-domain transfer learning: An experimental study. Despotovic V, Kim SY, Hau AC, Kakoichankava A, Klamminger GG, Borgmann FBK, Frauenknecht KBM, Mittelbronn M, Nazarov PV. Heliyon. 2024 Mar 6;10(5):e27515. doi: 10.1016/j.heliyon.2024.e27515. eCollection 2024 Mar 15. PMID: 38562501
Impact of Formalin- and Cryofixation on Raman Spectra of Human Tissues and Strategies for Tumor Bank Inclusion. Mirizzi G, Jelke F, Pilot M, Klein K, Klamminger GG, Gérardy JJ, Theodoropoulou M, Mombaerts L, Husch A, Mittelbronn M, Hertel F, Kleine Borgmann FB. Molecules. 2024 Mar 6;29(5):1167. doi: 10.3390/molecules29051167. PMID: 38474679
Computational Assessment of Spectral Heterogeneity within Fresh Glioblastoma Tissue Using Raman Spectroscopy and Machine Learning Algorithms. Klein K, Klamminger GG, Mombaerts L, Jelke F, Arroteia IF, Slimani R, Mirizzi G, Husch A, Frauenknecht KBM, Mittelbronn M, Hertel F, Kleine Borgmann FB. Molecules. 2024 Feb 23;29(5):979. doi: 10.3390/molecules29050979. PMID: 38474491
Blocking TGF-β- and Epithelial-to-Mesenchymal Transition (EMT)-mediated activation of vessel-associated mural cells in glioblastoma impacts tumor angiogenesis. Merk L, Regel K, Eckhardt H, Evers M, El-Ayoubi A, Mittelbronn M, Krüger M, Gérardy JJ, Mack AF, Naumann U. Free Neuropathol. 2024 Mar 1;5:4. doi: 10.17879/freeneuropathology-2024-5188. eCollection 2024 Jan. PMID: 38455669
Cell adhesion affects the properties of interstitial fluid flow: A study using multiscale poroelastic composite modeling. Dehghani H, Holzapfel GA, Mittelbronn M, Zilian A. J Mech Behav Biomed Mater. 2024 May;153:106486. doi: 10.1016/j.jmbbm.2024.106486. Epub 2024 Feb 27. PMID: 38428205
CLN3 deficiency leads to neurological and metabolic perturbations during early development. Heins-Marroquin U, Singh RR, Perathoner S, Gavotto F, Merino Ruiz C, Patraskaki M, Gomez-Giro G, Kleine Borgmann F, Meyer M, Carpentier A, Warmoes MO, Jäger C, Mittelbronn M, Schwamborn JC, Cordero-Maldonado ML, Crawford AD, Schymanski EL, Linster CL. Life Sci Alliance. 2024 Jan 9;7(3):e202302057. doi: 10.26508/lsa.202302057. Print 2024 Mar. PMID: 38195117

National Center of Genetics

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Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors.
Willim J, Woike D, Greene D, Das S, Pfeifer K, Yuan W, Lindsey A, Itani O, Böhme AL, Tibbe D, Hönck HH, Hassani Nia F; Undiagnosed Diseases Network; Zech M, Brunet T, Faivre L, Sorlin A, Vitobello A, Smol T, Colson C, Baranano K, Schatz K, Bayat A, Schoch K, Spillmann R, Davis EE, Conboy E, Vetrini F, Platzer K, Neuser S, Gburek-Augustat J, Grace AN, Mitchell B, Stegmann A, Sinnema M, Meeks N, Saunders C, Cadieux-Dion M, Hoyer J, Van-Gils J, de Sainte-Agathe JM, Thompson ML, Bebin EM, Weisz-Hubshman M, Tabet AC, Verloes A, Levy J, Latypova X, Harder S, Silverman GA, Pak SC, Schedl T, Freson K, Mumford A, Turro E, Schlein C, Shashi V, Kreienkamp HJ. Nat Commun. 2024 Sep 10;15(1):7909. doi: 10.1038/s41467-024-52095-x. PMID: 39256359; PMCID: PMC11387733.
Variants of NAV3, a neuronal morphogenesis protein, cause intellectual disability, developmental delay, and microcephaly.
Ghaffar A, Akhter T, Strømme P, Misceo D, Khan A, Frengen E, Umair M, Isidor B, Cogné B, Khan AA, Bruel AL, Sorlin A, Kuentz P, Chiaverini C, Innes AM, Zech M, Baláž M, Havrankova P, Jech R, Ahmed ZM, Riazuddin S, Riazuddin S. Commun Biol. 2024 Jul 8;7(1):831. doi:10.1038/s42003-024-06466-1. PMID: 38977784; PMCID: PMC11231287.
Expectations, needs and mid-term outcomes in people accessing to secondary findings from ES: 1st French mixed study (FIND Study).
Viora-Dupont E, Robert F, Chassagne A, Pélissier A, Staraci S, Sanlaville D, Edery P, Lesca G, Putoux A, Pons L, Cadenes A, Baurand A, Sawka C, Bertolone G, Spetchian M, Yousfi M, Salvi D, Gautier E, Vitobello A, Denommé-Pichon AS, Bruel AL, Tran Mau-Them F, Faudet A, Keren B, Labalme A, Chatron N, Abel C, Dupuis-Girod S, Poisson A, Buratti J, Mignot C, Afenjar A, Whalen S, Charles P, Heide S, Mouthon L, Moutton S, Sorlin A, Nambot S, Briffaut AS, Asensio ML, Philippe C, Thauvin-Robinet C, Héron D, Rossi M, Meunier-Bellard N, Gargiulo M, Peyron C, Binquet C, Faivre L. Eur J Hum Genet. 2024 Sep;32(9):1166-1183. doi: 10.1038/s41431-024-01616-9. PMID: 38802530; PMCID: PMC11368951.
Unveiling the crucial neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathies.
Küry S, Stanton JE, van Woerden G, Hsieh TC, Rosenfelt C, Scott-Boyer MP, Most V, Wang T, Papendorf JJ, de Konink C, Deb W, Vignard V, Studencka-Turski M, Besnard T, Hajdukowicz AM, Thiel F, Möller S, Florenceau L, Cuinat S, Marsac S, Wentzensen I, Tuttle A, Forster C, Striesow J, Golnik R, Ortiz D, Jenkins L, Rosenfeld JA, Ziegler A, Houdayer C, Bonneau D, Torti E, Begtrup A, Monaghan KG, Mullegama SV, Volker-Touw CMLN, van Gassen KLI, Oegema R, de Pagter M, Steindl K, Rauch A, Ivanovski I, McDonald K, Boothe E, Dauber A, Baker J, Fabie NAV, Bernier RA, Turner TN, Srivastava S, Dies KA, Swanson L, Costin C, Jobling RK, Pappas J, Rabin R, Niyazov D, Tsai AC, Kovak K, Beck DB, Malicdan M, Adams DR, Wolfe L, Ganetzky RD, Muraresku C, Babikyan D, Sedláček Z, Hančárová M, Timberlake AT, Al Saif H, Nestler B, King K, Hajianpour MJ, Costain G, Prendergast D, Li C, Geneviève D, Vitobello A, Sorlin A, Philippe C, Harel T, Toker O, Sabir A, Lim D, Hamilton M, Bryson L, Cleary E, Weber S, Hoffman TL, Cueto-González AM, Tizzano EF, Gómez-Andrés D, Codina-Solà M, Ververi A, Pavlidou E, Lambropoulos A, Garganis K, Rio M, Levy J, Jurgensmeyer S, McRae AM, Lessard MK, D’Agostino MD, De Bie I, Wegler M, Jamra RA, Kamphausen SB, Bothe V, Busch LM, Völker U, Hammer E, Wende K, Cogné B, Isidor B, Meiler J, Bosc-Rosati A, Marcoux J, Bousquet MP, Poschmann J, Laumonnier F, Hildebrand PW, Eichler EE, McWalter K, Krawitz PM, Droit A, Elgersma Y, Grabrucker AM, Bolduc FV, Bézieau S, Ebstein F, Krüger E. medRxiv [Preprint]. 2024 Jan 26:2024.01.13.24301174. doi:10.1101/2024.01.13.24301174. PMID: 38293138; PMCID: PMC10827246.
Clinico-biological refinement of BCL11B-related disorder and identification of an episignature: A series of 20 unreported individuals.
Sabbagh Q, Haghshenas S, Piard J, Trouvé C, Amiel J, Attié-Bitach T, Balci T, Barat-Houari M, Belonis A, Boute O, Brightman DS, Bruel AL, Caraffi SG, Chatron N, Collet C, Dufour W, Edery P, Fong CT, Fusco C, Gatinois V, Gouy E, Guerrot AM, Heide S, Joshi A, Karp N, Keren B, Lesieur-Sebellin M, Levy J, Levy MA, Lozano C, Lyonnet S, Margot H, Marzin P, McConkey H, Michaud V, Nicolas G, Nizard M, Paulet A, Peluso F, Pernin V, Perrin L, Philippe C, Prasad C, Prasad M, Relator R, Rio M, Rondeau S, Ruault V, Ruiz-Pallares N, Sanchez E, Shears D, Siu VM, Sorlin A, Tedder M, Tharreau M, Mau-Them FT, van der Laan L, Van Gils J, Verloes A, Whalen S, Willems M, Yauy K, Zuntini R, Kerkhof J, Sadikovic B, Geneviève D. Genet Med. 2024 Jan;26(1):101007. doi: 10.1016/j.gim.2023.101007. PMID: 37860968.
Genetic evaluation of patients with multiple primary cancers.
Freire MV, Thissen R, Martin M, Fasquelle C, Helou L, Durkin K, Artesi M, Lumaka A, Leroi N, Segers K, Deberg M, Gatot JS, Habran L, Palmeira L, Josse C, Bours V. Oncol Lett. 2024 Oct 15;29(1):4. doi: 10.3892/ol.2024.14750. PMID: 39492936; PMCID: PMC11526284.
Digenic Inheritance of Mutations in Homologous Recombination Genes in Cancer Patients.
Freire MV, Martin M, Segers K, Sepulchre E, Leroi N, Coupier J, Kalantari HR, Wolter P, Collignon J, Polus M, Plomteux O, Josse C, Bours V. J Pers Med. 2024 May 29;14(6):584. doi: 10.3390/jpm14060584. PMID: 38929805; PMCID: PMC11204488.
A step-by-step, multidisciplinary strategy to maximize the yield of genetic testing in pediatric patients with chronic kidney diseases.
Caliment A, Van Reeth O, Hougardy C, Dahan K, Niel O.
Pediatr Nephrol. 2024 Sep;39(9):2733-2740. doi: 10.1007/s00467-024-06299-4. PMID: 38316682.
Molecular consequences of PQBP1 deficiency, involved in the X-linked Renpenning syndrome.
Courraud J, Engel C, Quartier A, Drouot N, Houessou U, Plassard D, Sorlin A, Brischoux-Boucher E, Gouy E, Van Maldergem L, Rossi M, Lesca G, Edery P, Putoux A, Bilan F, Gilbert-Dussardier B, Atallah I, Kalscheuer VM, Mandel JL, Piton A.
Mol Psychiatry. 2024 Feb;29(2):287-296. doi:10.1038/s41380-023-02323-5. PMID: 38030819.
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts.
Yabo YA, Moreno-Sanchez PM, Pires-Afonso Y, Kaoma T, Nosirov B, Scafidi A, Ermini L, Lipsa A, Oudin A, Kyriakis D, Grzyb K, Poovathingal SK, Poli A, Muller A, Toth R, Klink B, Berchem G, Berthold C, Hertel F, Mittelbronn M, Heiland DH, Skupin A, Nazarov PV, Niclou SP, Michelucci A, Golebiewska A.
Genome Med. 2024 Apr 2;16(1):51. doi:10.1186/s13073-024-01321-8. PMID: 38566128; PMCID: PMC10988817.
The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions.
Xue Z, Zhang Y, Zhao R, Liu X, Grützmann K, Klink B, Zhang X, Wang S, Zhao W, Sun Y, Han M, Wang X, Hu Y, Liu X, Yang N, Qiu C, Li W, Huang B, Li X, Bjerkvig R, Wang J, Zhou W.
J Exp Clin Cancer Res. 2024 Jan 22;43(1):25. doi: 10.1186/s13046-024-02947-7. PMID: 38246990; PMCID: PMC10801958.
Upregulation versus loss of function of NTRK2 in 44 affected individuals leads to 2 distinct neurodevelopmental disorders.
Berger E, Jauss RT, Ranells JD, Zonic E, von Wintzingerode L, Wilson A, Wagner J, Tuttle A, Thomas-Wilson A, Schulte B, Rabin R, Pappas J, Odgis JA, Muthaffar O, Mendez-Fadol A, Lynch M, Levy J, Lehalle D, Lake NJ, Krey I, Kozenko M, Knierim E, Jouret G, Jobanputra V, Isidor B, Hunt D, Hsieh TC, Holtz AM, Haack TB, Gold NB, Dunstheimer D, Donge M, Deb W, De La Rosa Poueriet KA, Danyel M, Christodoulou J, Chopra S, Callewaert B, Busche A, Brick L, Bigay BG, Arlt M, Anikar SS, Almohammal MN, Almanza D, Alhashem A, Bertoli-Avella A, Sticht H, Abou Jamra R.
Genet Med. 2024 Nov 12:101326. doi: 10.1016/j.gim.2024.101326. PMID: 39540377.
Natural history of adults with KBG syndrome: A physician-reported experience.
Bayat A, Grimes H, de Boer E, Herlin MK, Dahl RS, Lund ICB, Bayat M, Bolund ACS, Gjerulfsen CE, Gregersen PA, Zilmer M, Juhl S, Cebula K, Rahikkala E, Maystadt I, Peron A, Vignoli A, Alfano RM, Stanzial F, Benedicenti F, Currò A, Luk HM, Jouret G, Zurita E, Heuft L, Schnabel F, Busche A, Veenstra-Knol HE, Tkemaladze T, Vrielynck P, Lederer D, Platzer K, Ockeloen CW, Goel H, Low KJ. Genet Med. 2024 Aug;26(8):101170. doi: 10.1016/j.gim.2024.101170. Epub 2024 May 27. PMID: 38818797.
Recurrence of Phospholipase A2 Receptor-Associated Membranous Nephropathy in the Absence of Serum Anti-Phospholipase A2 Receptor Antibodies Reappearance.
Bensouna I, Delafosse M, Cartery C, Stehlé T, Rabate C, Boullenger F, Buob D, Boffa JJ, Dahan K, Esteve E.
Kidney Int Rep. 2024 Dec 10;10(3):952-955. doi: 10.1016/j.ekir.2024.12.009. PMID: 40225389; PMCID: PMC11993193.
K acetyltransferase 2B (KAT2B) variants can be responsible for early onset steroid-resistant nephrotic syndrome.
Niel O, Caliment A, Hougardy C, Monestier O, Dahan K.
J Med Genet. 2024 Nov 25;61(12):1113-1115. doi: 10.1136/jmg-2024-110142. PMID: 39366742.
Genetic counselling legislation and practice in cancer in EU Member States.
McCrary JM, Van Valckenborgh E, Poirel HA, de Putter R, van Rooij J, Horgan D, Dierks ML, Antonova O, Brunet J, Chirita-Emandi A, Colas C, Dalmas M, Ehrencrona H, Grima C, Janavičius R, Klink B, Koczok K, Krajc M, Lace B, Leitsalu L, Mistrik M, Paneque M, Primorac D, Roetzer KM, Ronez J, Slámová L, Spanou E, Stamatopoulos K, Stoklosa T, Strang-Karlsson S, Szakszon K, Szczałuba K, Turner J, van Dooren MF, van Zelst-Stams WAG, Vassallo LM, Wadt KAW, Žigman T, Ripperger T, Genuardi M, Van den Bulcke M, Bergmann AK.
Eur J Public Health. 2024 Aug 1;34(4):666-675. doi: 10.1093/eurpub/ckae093. PMID: 38905592; PMCID: PMC11293827.

Medical Biology

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Microbiology

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Kohlenberg A, Svartström O, Apfalter P, Hartl R, Bogaerts P, Huang TD, Chudejova K, Malisova L, Eisfeld J, Sandfort M, Hammerum AM, Roer L, Räisänen K, Dortet L, Bonnin RA, Tóth Á, Tóth K, Clarke C, Cormican M, Griškevičius A, Khonyongwa K, Meo M, Niedre-Otomere B, Vangravs R, Hendrickx AP, Notermans DW, Samuelsen Ø, Caniça M, Manageiro V, Müller V, Mäkitalo B, Kramar U, Pirs M, Palm D, Monnet DL, Alm E, Linkevicius Emergence of E.coli ST131 carrying carbapenemase genes, European Union/EEA, August 2012 to May 2024 Euro Surveill. 2024 Nov;29(47):2400727. doi: 10.2807/15
Shaw D, Torreblanca RA, Amin-Chowdhury Z, Bautista A, Bennett D, Broughton K, Casanova C, Choi EH, Claus H, Corcoran M, Cottrell S, Cunney R, Cuypers L, Dalby T, Davies H, de Gouveia L, Deghmane AE, Desmet S, Domenech M, Drew R, Plessis MD, Duarte C, Fuursted K, Golden A, Almeida SCG, Henares D, Henriques-Normark B, Hilty M, Hoffmann S, Humphreys H, Jacobsson S, Johnson C, Jolley KA, Kawabata A, Kozakova J, Kristinsson KG, Krizova P, Kuch A, Ladhani S, Lâm TT, Ayala MEL, Lindholm L, Litt D, Maiden MCJ, Martin I, Martiny D, Mattheus W, McCarthy ND, Meehan M, Meiring S, Mölling P, Morfeldt E, Morgan J, Mulhall R, Muñoz-Almagro C, Murdoch D, Musilek M, Novakova L, Oftadeh S, Perez-Arguello A, Pérez-Vázquez MD, Perrin M, Prevost B, Roberts M, Rokney A, Ron M, Sanabria OM, Scott KJ, Sempere J, Siira L, de Lemos APS, Sintchenko V, Skoczyńska A, Slotved HC, Smith AJ, Taha MK, Toropainen M, Tzanakaki G, Vainio A, van der Linden MPG, van Sorge NM, Varon E, Moreno JV, Vohrnova S, von Gottberg A, Yuste J, Brueggemann AB. The importance of microbiology reference laboratories and adequate funding for infectious disease surveillance Lancet Digit Health. 2024 Dec 20:S2589-7500(24)00241-3. doi: 10.1016/S2589-7500(24)00241-3.
Moore HL, Aabye M, Hoban A, Rosner B, Lefevre SK, Litrup E, Müller L, Ethelberg S, Simon S, Balasegaram S, Larkin L, Jernberg C, Takkinen J; EU/EEA/UK S. Braenderup Outbreak Investigation Group; Members of the EU/EEA/UK S. Braenderup Outbreak Investigation Group Multinational collaboration in solving a European Salmonella Braenderup outbreak linked to imported melons, 2021 Euro Surveill. 2024 Jan;29(1):2300273. doi: 10.2807/1560-7917.ES.2024.29.1.2300273. PMID: 38179625; PMCID: PMC10905663.
Hock L, Walczak C, Mosser J, Ragimbeau C, Cauchie HM Exploring the Role of the Environment as a Reservoir of Antimicrobial-Resistant Campylobacter: Insights from Wild Birds and Surface Waters. Microorganisms. 2024 Aug 8;12(8):1621. doi: 10.3390/microorganisms12081621. PMID: 39203463; PMCID: PMC11356556.
Citation style for this article: Broberg Eeva K, Vukovikj Maja, Svartström Olov, Hasibra Iris, Riess Maximilian, Melidou Angeliki, Members of the ERLI-Net network Antigenic changes in influenza A(H3N2) driven by genetic evolution: Insights from virological surveillance, EU/EEA, week 40/2023 to week 9/2024. Euro Surveill. 2024;29(50):pii=2400395. https://doi.org/10.2807/1560-7917.ES.2024.29.50.2400395

Health Protection

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Gonçalves, A., Leitão, M. , Fernandes, J., Saavedra, MJ, Pereira, C, Simões, M., Borges, A (2024). Photodynamic activation of phytochemical-antibiotic combinations for combatting Staphylococcus aureus from acute wound infections. Journal of Photochemistry and Photobiology B: Biology, (258) 112978. https://doi.org/10.1016/j.jphotobiol.2024.112978
Amanda Fernandes, Demetris Avraam, Tim Cadman, Payam Dadvand, Mònica Guxens, Anne-Claire Binter, Angela Pinot de Moira, Mark Nieuwenhuijsen, Liesbeth Duijts, Jordi Julvez, Montserrat De Castro, Serena Fossati, Sandra Márquez, Tanja Vrijkotte, Ahmed Elhakeem, Rosemary McEachan, Tiffany Yang, Marie Pedersen, Johan Vinther, Johanna Lepeule, Barbara Heude, Vincent W V Jaddoe, Susana Santos, Marieke Welten, Hanan El Marroun, Annemiek Mian, Sandra Andrušaitytė, Aitana Lertxundi, Jesús Ibarluzea, Ferran Ballester, Ana Esplugues, Maria Torres Toda, Jennifer R Harris, Johanna Lucia Thorbjørnsrud Nader, Giovenale Moirano, Silvia Maritano, Rebecca Catherine Wilson, Martine Vrijheid. (2024). Green spaces and respiratory, cardiometabolic, and neurodevelopmental outcomes: An individual-participant data meta-analysis of >35.000 European children. Environ Int. 2024 Aug:190:108853. https://doi:10.1016/j.envint.2024.108853
Creta, M., Verscheure, E., Tans, B., Devriese, H., Devriendt, A., Devolder, D., Lebegge, R., Poels, K., Godderis, L., Duca, R-C., Vanoirbeek, J.A J. (2024). An Assessment of Surface Contamination and Dermal Exposure to 5-Fluorouracil in Healthcare Settings by UPLC-MS/MS Using a New Atmospheric Pressure Ionization Source. Toxics, 12 (11), 766. https//doi: 10.3390/toxics12110766 Access via repository
Hopf, N.B., Rousselle, C., Poddalgoda, D., Lamkarkach, F., Bessems, J., Schmid, K., Jones, K., Takaki, K., Casteleyn, L., Jeddi, M.Z., Bader, M., Koller, M., Browne, P., Fitzgerald, R., Viegas, S., Goeen, T., Santonen, T., Vaananen, V., Duca, R-C., Pasanen-Kase, R. (2024). A harmonized occupational biomonitoring approach. Environment International, 191, 108990. https//doi: 10.1016/j.envint.2024.108990
De Nys, S., Turkalj, M., Duca, R.C., Covaci, A., Elskens, M., Godderis, L., Vanoirbeek, J., Van Meerbeek, B., Landuyt, K.L V. with Landuyt, K.L V. (2024). Level of BPA contamination in resin composites determines BPA release. Dental Materials, 40 (7), 1025-1030. doi: 10.1016/j.dental.2024.05.006
Cseresznye, A., Hardy, E.M., Bamai, Y.A., Cleys, P., Poma, G., Malarvannan, G., Scheepers, P.T J., Viegas, S., Martins, C., Porras, S.P., Santonen, T., Godderis, L., Verdonck, J., Poels, K., Silva, M.J., Louro, H., Martinsone, I., Akulova, L., van Dael, M., van Nieuwenhuyse, A., Mahiout, S., Duca, R.C., Covaci, A. (2024). HBM4EU E-waste study: Assessing persistent organic pollutants in blood, silicone wristbands, and settled dust among E-waste recycling workers in Europe. Environmental Research, 250, 118537. doi: 10.1016/j.envres.2024.118537
Tralec, Z., Antignac, J-P., Bandow, N., Been, F.M., Belova, L., Bessems, J., Le Bizec, B., Brack, W., Cano-Sancho, G., Chaker, J., Covaci, A., Creusot, N., David, A., Debrauwer, L., Dervilly, G., Duca, R.C., Fessard, V., Grimalt, J.O., Guerin, T., Habchi, B., Hecht, H., Hollender, J., Jamin, E.L., Klanova, J., Kosjek, T., Krauss, M., Lamoree, M., Lavison-Bompard, G., Meijer, J., Moeller, R., Mol, H., Mompelat, S., Van Nieuwenhuyse, A., Oberacher, H., Parinet, J., Van Poucke, C., Roskar, R., Togola, A., Trontelj, J., Price, E.J. (2024). Innovative analytical methodologies for characterizing chemical exposure with a view to next-generation risk assessment. Environment International, 186, 108585. doi: 10.1016/j.envint.2024.108585 Open Access
Reale, E., Jeddi, M.Z., Paini, A., Connolly, A., Duca, R., Cubadda, F., Benfenati, E., Bessems, J., Galea, K.S., Dirven, H., Santonen, T., Koch, H.M., Jones, K., Sams, C., Viegas, S., Kyriaki, M., Campisi, L., David, A., Antignac, J-P., Hopf, N.B. with Hopf, N.B. (corresp. author) (2024). Human biomonitoring and toxicokinetics as key building blocks for next generation risk assessment. Environment International, 184, 108474. doi: 10.1016/j.envint.2024.108474
Musa Obadia P, Milambo Kapia P, Bonneure A, Duca RC, Creta M, Kayembe-Kitenge T, Tytgat J, Okitundu D, Banza Lubaba Nkulu C, Nemery B. Bombé, an undetermined substance that caused an outbreak of illicit drug use in Kinshasa, Democratic Republic of the Congo. Clin Toxicol (Phila). 2023 Dec 4:1-4. doi: 10.1080/15563650.2023.2276040. Epub ahead of print. PMID: 38047882.
Rani Claus, Wai Kei Chu, Luke D. Savory, Astrid Staelens, Katrien Poels, Mike Draper, Matteo Creta, Jeroen A.J. Vanoirbeek, Comparison of a novel glove connector to chemical tape as a sealing device between gloves and protection suits, Journal of Hazardous Materials, Volume 476, 2024, 135186, ISSN 0304-3894, https://doi.org/10.1016/j.jhazmat.2024.135186.
Cuffaro, F., Dahm, G., Marson, C., Berlemont, P., Yegles, M., Allar, C., Fauchet, L., Creta, M., Schneider, S., 2024. Contamination of a drug consumption room with drugs and potential risks for social health care workers. https://doi.org/10.21203/rs.3.rs-3978967/v1
Eline Verscheure, Ilana Struys, Matteo Creta, Katrien Poels, Jeroen Vanoirbeek, Liesbeth Lenaerts, Frédéric Amant, Manosij Ghosh & Lode Godderis. Development and validation of an UPLC-ESI–MS/MS method for simultaneous quantification of antineoplastic agents and their metabolites in human plasma after unintentional exposure. Arch Toxicol (2024). https://doi.org/10.1007/s00204-024-03900-5.
Eline Verscheure, Matteo Creta, Katrien Poels, Jeroen Vanoirbeek, Manosij Ghosh, Lode Godderis. Quantification of five antineoplastic agents in swab samples using UPLC-ESI-MS/MS: method development and validation, Analytica Chimica Acta, 2024, 343492, ISSN 0003-2670, https://doi.org/10.1016/j.aca.2024.343492
Cleys, P., Hardy, E., Bamai, Y.A., Poma, G., Cseresznye, A., Malarvannan, G., Scheepers, P.T J., Viegas, S., Porras, S.P., Santonen, T., Godderis, L., Verdonck, J., Poels, K., Martins, C., Silva, M.J., Louro, H., Martinsone, I., Akulova, L., Van Nieuwenhuyse, A., Graumans, M., Mahiout, S., Duca, R.C., Covaci, A. (2024). HBM4EU e-waste study: Occupational exposure of electronic waste workers to phthalates and DINCH in Europe. International Journal of Hygiene And Environmental Health, 255, 114286. doi: 10.1016/j.ijheh.2023.114286
Morel, C., Paoli, J., Emond, C., Debaugnies, F., Hardy, E.M., Creta, M., Montagne, M., Borde, P., Van Nieuwenhuyse, A., Duca, R.C., Schroeder, H., Grova, N. (2024). Pharmacokinetic characterisation of a valproate Autism Spectrum Disorder rat model in a context of co-exposure to α-Hexabromocyclododecane. Environmental Toxicology And Pharmacology, 105, 104343. doi: 10.1016/j.etap.2023.104343
Chbihi, K., Menouni, A., Hardy, E., Creta, M., Grova, N., Van Nieuwenhuyse, A., Godderis, L., El Jaafari, S., Duca, R-C. (2024). Exposure of children to brominated flame retardants and heavy metals in Morocco: Urine and blood levels in association with global cytosine and adenine methylation. Environment International, 183, 108409. doi: 10.1016/j.envint.2023
Namorado S., Martins C., Ogura J., Assunção R., Vasco E., Appenzeller B., I Halldorsson T., Janasik B., Kolossa-Gehring M., Van Nieuwenhuyse A., Ólafsdóttir K., Rambaud L., Riou M., Silva S., Wasowicz W., Weber T., Esteban-López M., Castaño A., Gilles L., Rodríguez Martin L., Govarts E., Schoeters G., Viegas S., Silva MJ., Alvito P. Exposure assessment of the European adult population to deoxynivalenol – Results from the HBM4EU Aligned Studies. Food Res Int. 2024 Dec;198:115281. doi: 10.1016/j.foodres.2024.115281. Epub 2024 Nov 6. PMID: 39643334.
Galea KS., Paini A., Bachler G., Alejandre-Colomo C., Fantke P., Fransman W., Jung C., Van Nieuwenhuyse A., von Goetz N., Connolly A. Reflection on the landscape of education in the area of exposure modelling. Environment International. 2024 Nov;193:109103. doi: 10.1016/j.envint.2024.109103. Epub 2024 Oct 28. PMID: 39486252.
Tagne-Fotso R., Riou M., Saoudi A., Zeghnoun A., Frederiksen H., Berman T., Montazeri P., Andersson AM., Rodriguez-Martin L., Akesson A., Berglund M., Biot P., Castaño A., Charles MA., Cocco E., Den Hond E., Dewolf MC., Esteban-Lopez M., Gilles L., Govarts E., Guignard C., Gutleb AC., Hartmann C., Kold Jensen T., Koppen G., Kosjek T., Lambrechts N., McEachan R., Sakhi AK., Snoj Tratnik J., Uhl M., Urquiza J., Vafeiadi M., Van Nieuwenhuyse A., Vrijheid M., Weber T., Zaros C., Tarroja-Aulina E., Knudsen LE., Covaci A., Barouki R., Kolossa-Gehring M., Schoeters G., Denys S., Fillol C., Rambaud L. Exposure to bisphenol A in European women from 2007 to 2014 using human biomonitoring data – The European Joint Programme HBM4EU. Environment International. 2024 Aug;190:108912. doi: 10.1016/j.envint.2024.108912. Epub 2024 Jul 25. PMID: 39116556.
Schaeffer C., Schummer C., Scholer S., van Nieuwenhuyse A., Pincemaille J. Evaluation of environmental contamination in beeswax products. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Aug 15;1244:124243. doi: 10.1016/j.jchromb.2024.124243. Epub 2024 Jul 20. PMID: 39068867.
F Fernández S., Poteser M., Govarts E., Pardo O., Coscollà C., Schettgen T., Vogel N., Weber T., Murawski A., Kolossa-Gehring M., Rüther M., Schmidt P., Namorado S., Van Nieuwenhuyse A., Appenzeller B., Ólafsdóttir K., Halldorsson TI., Haug LS., Thomsen C., Barbone F., Mariuz M., Rosolen V., Rambaud L., Riou M., Göen T., Nübler S., Schäfer M., Zarrabi KHA., Sepai O., Martin LR., Schoeters G., Gilles L., Leander K., Moshammer H., Akesson A., Laguzzi F. Publisher Correction: Determinants of exposure to acrylamide in European children and adults based on urinary biomarkers: results from the “European Human Biomonitoring Initiative” HBM4EU participating studies. Sci Rep. 2024 Jan 29;14(1):2405. doi: 10.1038/s41598-024-52775-0. Erratum for: Sci Rep. 2023 Dec 2;13(1):21291. doi: 10.1038/s41598-023-48738-6. PMID: 38287129; PMCID: PMC10825204.
Lamon, J. Doyle, A. Paini, R. Moeller, S. Viegas, F. Cubadda, P. Hoet, A. Van Nieuwenhuyse, H. Louro, M Dusinska, K.S. Galea, R. Canham, C. Martins, A. Gama, V. Teófilo, M. Diniz-da-Costa, M. João Silva, C. Ventura, P. Alvito, N. El Yamani, M. Ghosh, R.C. Duca, M. Siccardi, E. Runden-Pran, C. McNamara, P. Price. (2024) Roadmap for action for advancing aggregate exposure to chemicals in the EU. EFSA supporting publication 2024:EN-8971.364pp doi:10.2903/sp.efsa.2024.EN-8971
Andjelkovic M, Van Overmeire I, Joly L, Poma G, Malarvannan G, Vleminckx C, Malysheva SV, Vanhouche M, Van Loco J, Van Nieuwenhuyse A, Covaci A. Persistent organic pollutants in human milk of Belgian mothers: levels, time trend and exposure assessment for nursing infants. J Environ Expo Assess 2024;3:23. https://dx.doi.org/10.20517/jeea.2024.22

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